Scientist, Immunogenicity, Bioanalytical and Molecular Assays

The Role:

Joining Moderna offers the unique opportunity to be part of a pioneering team that's revolutionizing medicine through mRNA technology with a diverse pipeline of development programs across various diseases. As an employee, you'll be part of a continually growing organization working alongside exceptional colleagues and strategic partners worldwide, contributing to global health initiatives. Moderna's commitment to advancing the technological frontier of mRNA medicines ensures a challenging and rewarding career experience with the potential to make a significant impact on patients' lives worldwide

Moderna's mission is to establish a leading-edge research, development, and manufacturing facility at Harwell as part of a long-term commitment to onshore mRNA vaccine production for respiratory diseases. This initiative will create a multitude of highly skilled jobs and foster collaboration with academic, NHS, and government partners across the UK. We're looking for global experts eager to join us in this endeavour, contributing to a future where access to life-saving vaccines is a reality for all.

Moderna is seeking an experienced Bioanalytical Scientist to join the Bioanalytical and Molecular Assays team to support regulated clinical trials. This role is essential in integrating basic science research, bioanalysis, and informatics to move programs into the clinic and reverse-engineer clinical findings for new opportunities in Moderna’s pipeline. The role will require the design and execution of bioanalytical strategies while managing internal and external collaborations to develop and validate assays that are crucial for clinical success.

Here's What Youll Do:

Your key responsibilities will be:

• Design and execute phase-appropriate bioanalytical strategies, including immunogenicity (anti-drug antibodies and neutralizing antibody assays) and quantitation of therapeutic proteins (PK/PD assay) method development.
• Ensure assays are developed on time, meet regulatory standards, and troubleshoot any issues internally or with external CRO partners.
• Develop various assays using ELISA, MSD, cell culture, immunoblotting, and other relevant technologies.
  
  
  

Your responsibilities will also include:

• Establish internal and external ASO bioanalytical capabilities and facilitate method development to support Moderna’s portfolio.
• Manage analytical equipment procurement/qualifications, prepare and maintain SOPs, and oversee critical reagents.
• Collaborate with preclinical and clinical operations to define sample journeys and develop laboratory manuals.
• Set up analytical LIMS profiles for sample analysis and assay validations.
  
  
  

The key Moderna Mindsets you’ll need to succeed in the role:

• Prioritize the platform: In this role, you will need to focus on leveraging Moderna’s platform to ensure assays are fit for purpose and align with the broader goal of advancing mRNA-based therapeutics.
• Question convention: You will be expected to challenge existing methodologies and continuously seek new ways to improve bioanalytical strategies in line with regulatory and scientific advancements.
  
  
  

Here’s What You’ll Bring To The Table

• A Ph.D. with at least 3+ years or BSc. with 5+ years of demonstrated hands-on experience development and validation of bioanalytical methods in infectious disease, Immuno-oncology, Immunology, Cancer Biology, or related fields.
• Knowledge of GLP and GCP requirements and understanding of current industry trends and regulatory expectations associated with bioanalytical science.
• Expert knowledge of various assay platforms such as ECL, Cell culture, immunoassays, bDNA and other methodologies for clinical assays is preferred
• Hands-on experience in cell culture assays is an advantage
• Experience with RNA, biologics and cell therapy preferred
• Expert knowledge of Watson LIMS
• Willingness to learn new concepts and challenge boundaries
• Attention to detail and ability to handle multiple projects in a fast-paced environment 
• Experience using various LIMS systems is preferred
• Knowledge of FDA and global data standards required
• Ability to effectively communicate scientific concepts, program objectives, and data analysis within a matrix environment.
  
  
  

Moderna offers personalized benefit programs and well-being resources as unique as our global workforce so employees can do their best work.

We recognize and appreciate your diverse needs and interests and do our best to support you at work and at home with:

• Quality healthcare and insurance benefits
• Lifestyle Spending Accounts to create your own pathway to well-being
• Free premium access to fitness, nutrition, and mindfulness classes
• Family planning and adoption benefits
• Generous paid time off, including vacation, bank holidays, volunteer days, sabbatical, and a discretionary year-end shutdown
• Educational resources
• Savings and investments
• Location-specific perks and extras!
  
  
  

The benefits offered may vary depending on the nature of your employment with Moderna and the country where you work.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We’re focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations or adjustments to qualified job applicants with disabilities. Any applicant requiring an accommodation or adjustment in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should

contact the Accommodations and Adjustments team at [email protected].

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