Associate Principal Scientist, AMS Laboratory Operations

Job Introduction

Associate Principal Scientist, AMS Laboratory Operations

UK – Hoddesdon

Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services.

We’re proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. To learn more, visit www.pharmaron.com.

About the Role:

To continue our growth as a premier Contract Research Organisation, Pharmaron has opened a new Accelerator Mass Spectrometry (AMS) Laboratory at our Hoddesdon site. We are looking for an Associate Principal Scientist to join this new team. In this role, you will lead a team of scientists responsible for the analysis of samples and data generated from clinical AMS-enabled studies.

At Pharmaron we offer:

• Vibrant and dynamic employment – we are a highly specialised, growth company operating in a critical sector of the economy – our future is strong and exciting!
• Opportunities to develop your skills and yourself – our rapid growth brings greater opportunities for you to learn and grow faster!
• A great team where we all support each other – enjoy your work – after all you spend about a third of your time here!
  
  
  

Key roles and responsibilities:

• To be responsible for the day-to-day operation of the laboratories, ensuring that all GCP, quality and health and safety guidelines are met.
• To lead and co-ordinate the activities of the lab team responsible for the receipt and analysis of 14 C-labelled clinical samples by LSC, AMS, LC+AMS and LC-MS/MS.
• To understand (through hands-on laboratory training), and perform the analytical techniques and procedures involved in AMS-enabled clinical studies
• To assist (as needed) in the preparation and analysis samples and data generated from clinical AMS enabled studies, including mass balance, metabolite profiling and identification and IVPK (absolute bioavailability).
• To ensure that all equipment is validated, calibrated, maintained and serviced as per SOP
• To review study data and prepare summaries and updates for internal and external reporting
• Contribute to the review and QC checking of all relevant study data packages and reports prior to submission to Quality Assurance as required.
• Address findings appropriate to area arising from QA audits and process inspections.
• Plan work to ensure revenue recognition milestones on assigned studies are met and flagging up any issues early.
• To collaborate with other AMS team and Pharmaron stakeholders, providing regular status updates to ensure that project milestones are met.
• Actively contribute to client visits and teleconferences as appropriate.
• To collaborate with global AMS and metabolism teams and lead implementation of continuous improvement culture and efficiency optimization on behalf of the UK lab.
• Build a high performing, passionate team responsive to client needs through managing group objectives and coaching and mentoring junior team members.
  
  
  

Requirements:

• PhD, MSc or BSc (Hons) in Chemistry, Biochemistry, Physics or related subject
• Experience of managing or supervising a laboratory team within a GxP setting
• Experience of coordinating equipment validation, maintenance and calibration and scheduling of equipment workload to meet internal and external timelines
• Experience of working in drug discovery and/or development projects with appreciation of related disciplines
• Experience of managing scientific teams / coaching / mentoring
• Effective written and verbal communication skills, including the ability to effectively present scientific findings to colleagues and clients
• Effective problem solving and analysis skills
• Flexible mindset with the ability to take the initiative.
  
  
  

Why Pharmaron?

Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators.

How to Apply:

Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!

Pharmaron is a premier R&D service company supporting the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities having established diverse drug R&D service capabilities, ranging from synthetic, medicinal, and analytical chemistry, biology, DMPK, pharmacology, drug safety assessment, radiochemistry and isotopically labelled metabolism, chemical & pharmaceutical development to clinical development. With operations in China, US and UK staffed by over 19,000 employees, Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan, and China.